JC Virus Evolution and Its Association with Human Populations
نویسندگان
چکیده
منابع مشابه
JC virus evolution and its association with human populations.
The ubiquitous human polyomavirus JC (JCV) is a small double-stranded DNA virus that establishes a persistent infection, and it is often transmitted from parents to children. There are at least 14 subtypes of the virus associated with different human populations. Because of its presumed codivergence with humans, JCV has been used as a genetic marker for human evolution and migration. Codivergen...
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JC virus (JCV) is a human polyomavirus known as the causative agent of the fatal demyelinating disease, Progressive Multifocal Leukoencephalopathy (PML). Further, in experimental animals this virus causes a broad range of tumors of central nervous system origin. Recent studies have suggested the association of JCV with several human tumors most notably malignant brain tumors of childhood, medul...
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Association of Human Papilloma Virus and Epstein-Barr Virus with Ovarian Cancer in Shiraz, Southwestern Iran
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To the Editor: Newcomb et al. (1) have attempted to confirm the presence of JC virus (JCV) DNA in colorectal cancers and have failed to do so. They reached their negative conclusion, although other groups have been able show JCV in colonic epithelium and colorectal neoplasia (2-4). Whether this polyomavirus, which encodes a potent oncogene (T antigen), causes colon cancer remains an open questi...
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ژورنال
عنوان ژورنال: Journal of Virology
سال: 2006
ISSN: 0022-538X,1098-5514
DOI: 10.1128/jvi.00441-06